民 族

汉族

籍 贯

陕西乾县

最高学位

博士

职称/职务

副教授

社会兼职

联系方式

电话：18591921513

邮箱：masiyue@sust.edu.cn

学习及工作经历

主要研究方向

1. 荧光探针的设计合成及性能研究

2. 金属-氮杂环卡宾的催化反应研究

承担

的主

要项

目及

成果

参与及承担的项目：

[1] 急救与创伤研究教育部重点实验室开放基金，KLET-202010，基于荧光比率酶探针的急性胰腺炎标志物临床快速可视化检测，2021.01-2022.12，项目负责人；

[2] 陕西科技大学青年拔尖人才科研启动基金，126022085，比率型荧光探针合成及性能研究，2020.09-2024.09，项目负责人；

[3] 国家自然科学基金青年项目，21807087，肿瘤微环境激活型荧光探针构建及其光动力诊疗研究，2019.01-2021.12，参与人；

[4] 国家自然科学基金面上项目，21673173，多齿氮杂环金属卡宾MOFs多相催化材料的定向合成及其催化碳-杂偶联反应，2017.01-2020.12，参与人。

科研成果：

[1] Siyue Ma, Guang Chen*, Jie Xu, Yuxia Liu*, Guoliang Li, Tao Chen, Yulin Li, Tony D. James*, Current Strategies for the Development of Fluorescence-Based Molecular Probes for Visualizing the Enzymes and Proteins Associated with Alzheimer’s Disease. Coordination Chemistry Reviews 2021, 427, 213553. (IF = 15.367)

[2] Siyue Ma, Tongliang Zhou, Guangchen Li, Michal Szostak*, Suzuki‐Miyaura Cross‐Coupling of Amides Using Well‐Defined, Air‐Stable [(PR₃)₂Pd(II)X₂] Precatalysts. Advanced Synthesis & Catalysis 2020, 362, 1887-1892. (IF = 5.851)

[3] Siyue Ma^#, Jiabao Qiang^#, Linyang Li, Yan Mo, Mengyao She, Zheng Yang, Ping Liu, Shengyong Zhang, Jianli Li*, An Efficient Biosensor for Monitoring Alzheimer's Disease Risk Factors: Modulation and Disaggregation of the Aβ Aggregation Process. Journal of Materials Chemistry B 2019, 7, 4124-4132. (IF = 5.344)

[4] Siyue Ma^#, Linyang Li^#, Mengyao She, Yan Mo, Shengyong Zhang, Ping Liu, Jianli Li*, Synthesis and Application of Highly Sensitive Fluorescent Probe for Hg²⁺ Regulated by Sulfur. Chinese Chemical Letters 2017, 28, 2014-2018. (IF = 4.632)

[5] Siyue Ma^#, Zheng Yang^#, Mengyao She, Wei Sun, Bing Yin, Ping Liu, Shengyong Zhang, Jianli Li*, Design and Synthesis of Functionalized Rhodamine Based Probes for Specific Intracellular Fluorescence Imaging of Fe³⁺. Dyes and Pigments 2015, 115, 120-126. (IF = 4.613)

[6] Siyue Ma^#, Yaqi Wang^#, Mengyao She, Shen Wang, Zheng Yang, Ping Liu*, Shengyong Zhang, Jianli Li*, Design Strategies and Progress on Xanthene-Based Fluorescent Probe for Metal Ions. Reviews in Analytical Chemistry 2017, 36, 20160024. (IF = 2.174)

[7] Shen Wang, Siyue Ma, Jidong Zhang, Mengyao She, Ping Liu, Shengyong Zhang, Jianli Li*, A Highly Sensitive and Selective Near-Infrared Fluorescent Probe for Imaging Hydrazine in Living Tissues and Mice. Sensors and Actuators B: Chemical 2018, 261, 418-424. (IF = 7.1)

[8] Mengdi Liu, Siyue Ma, Mengyao She, Jiao Chen, Zhaohui Wang, Ping Liu, Shengyong Zhang, Jianli Li*, Structural Modification of BODIPY: Improve Its Applicability. Chinese Chemical Letters 2019, 30, 1815-1824. (IF = 4.632)

[9] Tongliang Zhou, Siyue Ma, Fady Nahra, Alan M. C. Obled, Albert Poater, Luigi Cavallo, Catherine S. J. Cazin, Steven P. Nolan, Michal Szostak*, [Pd(NHC)(μ-Cl)Cl]₂: Versatile and Highly Reactive Complexes for Cross-Coupling Reactions That Avoid Formation of Inactive Pd(I) Off-Cycle Products. iScience 2020, 23, 101377. (IF = 4.447)

[10] Guangchen Li, Siyue Ma, Michal Szostak*, Amide Bond Activation: The Power of Resonance. Trends in Chemistry 2020, 2, 914-928. (Cell Press)

[11] Zheng Yang, Mengyao She, Siyue Ma, Bing Yin, Ping Liu, Xiangrong Liu, Shunsheng Zhao, Jianli Li*, Rhodamine Based Guanidinobenzimidazole Functionalized Fluorescent Probe for Tetravalent Tin and Its Application in Living Cells Imaging. Sensors and Actuators B: Chemical 2017, 242, 872-879. (IF = 7.1)

[12] Zheng Yang*, Xinxin Bai, Siyue Ma, Xiangrong Liu, Shunsheng Zhao, Zaiwen Yang, A Benzoxazole Functionalized Fluorescent Probe for Selective Fe³⁺ Detection and Intracellular Imaging in Living Cells. Analytical Methods 2017, 9, 18-22. (IF = 2.596)

[13] Mengyao She, Shaoping Wu, Zhaohui Wang, Siyue Ma, Zheng Yang, Bing Yin, Ping Liu, Shengyong Zhang, Jianli Li*, Exploration of Congeneric Hg(II)-Mediated Chemosensors Driven by S-Hg Affinity and Their Application in Living System. Sensors and Actuators B: Chemical 2017, 247, 129-138. (IF = 7.1)