1.主要项目： n 国家自然科学基金（21505089），基于金磁微粒的即时检测用免疫探针的构建及微结构调控，2016.1-2018.12，主持 n 国家博士后第61批面上基金二等（202101710），Fe3O4纳米棒@Au微粒的化学组装及检测灵敏度调节，2018.1-2010.12，主持 n 陕西省重点研发计划一般项目（2022NY-042），纳米酶免疫层析技术用于苹果制品多菌灵残留膳食暴露评估的关键技术，2022.1-2023.12，主持 n 博士科研启动基金（BJ15-17），现场检测用磁性纳米免疫探针的构建与微结构调控机理研究，2016.1-2017.12，主持 n 陕西省科技计划面上项目（2012JM2003），纳米金磁微粒-寡核苷酸探针的构建及“自组装”实现目视化分型检测的机理研究，2013.1-2015.12，主持 n 国家自然科学基金（(21176149），酪素基中空微球皮革涂饰材料的微结构调控与性能研究，2012.1-2015.12，参与 n 陕西省教育厅专项科研计划项目（12JK0628），新型纳米Fe3O4/Au-寡核苷酸探针制备及用于目视化检测的研究，2012.1-2013.11，主持 n 国家自然科学(2100606)，基于表面引发ATRP法的聚合物刷/蒙脱土纳米复合材料结构与鞣制性能研究，2011.1-2013.12，参与 n 陕西省教育厅专项科研计划项目（06JK338）新型脂质-HAP-DNA复合物的制备及其在基因转染中的应用研究，2006.1-2010.11，主持 n 横向项目，分子印迹磁性微球在桦树茸活性成分提取中的应用研究，2021.6-2024.6，主持 2． 代表性论文： n Dong Yang*, Lei Lei, Kaidi Yang, Keyi Gao, Tongtong Jia, Lixia Wang, Xue Wang and Chaohua Xue*. An immunochromatography strip with peroxidase-mimicking ferric oxyhydroxide nanorods-mediated signal amplification and readout. Microchimica Acta. 2022, 189 (58). DOI: 10.1007/s00604-021-05085-5 n Dong Yang*, Keyi Gao, Baiqin Yang, Lei lei, Lixia Wang, Chaohua Xue*. Microfluidic synthesis of chitosan-coated magnetic alginate microparticles for controlled and sustained drug delivery [J]. Journal of International Biological Macromolecules, 2021, 182, 639-647. n Dong Yang*, Keyi Gao, Baiqin Yang, Lei lei, Lixia Wang, Chaohua Xue*. The classification of microfluidic system and applications in nanoparticles synthesis[J]. Progress in Chemistry, 2021, 33(3), 367-378. n Dong Yang*, Jianzhong Ma, Chaohua Xue*, et al. One-pot synthesis of poly(acrylic acid)-stabilized Fe3O4 nanocrystal cluster for the simultaneously qualitative and quantitative detection of biomarkers in lateral flow immunoassay[J]. Journal of Pharmaceutical and Biomedical Analysis. 2018, 159, 119-126. n Dong Yang, Jianzhong Ma*, Qinlu Zhang, Mingli Peng,Yanling Luo, Wenli Hui, Chao Chen and Yali Cui*. Polyelectrolyte coated gold magnetic nanoparticles for immunoassay development: toward point of care diagnositics [J]. Analytical Chemistry. 2013, 85(14), 6688-6695. n Dong Yang, Jianzhong Ma*, Min Gao, Yanling Luo, Wenli Hui, Chao Chen and Yali Cui*. Suppression of composite nanoparticle aggregation through steric stabilization and ligand exchange for colorimetric protein detection. RSC Advances. 2013, 3, 9681-9686. n Dong Yang, Jianzhong Ma*, Mingli Peng, Wenli Hui, Chao Chen and Yali Cui*. Building nanoSPR biosensor systems based on gold magnetic composite nanoparticles. Journal of Nanoscience and Nanotechnology. 2013, 13(8), 5485-5492. n Xue Wang, Dong Yang*, Shuntian Jia, Lingling Zhao, Tongtong Jia, Chaohua Xue*. Electrospun nitrocellulose membrane for immunochromatographic test strip with high sensitivity[J]. Microchimica Acta. 2020, 187 (12): 644. n Xiuxia Su*, Jia Xu, Jing Zhang, Dong Yang*, Chen He. Detection of cecropin B by liquid-crystal biosensor based on AuNPs signal amplification[J]. Liquid Crystals. 2020. 47(12): 1794-1802. n Xiuxia Su*, Wenjing Huo, Dong Yang, Chonglin Luan, Jia Xu. Label-free liquid crystal immunosensor for detection of HBD-2. Talanta, 2019, 203, 203-209. n Xiuxia Su*, Jiao Zhang, Dong Yang, Chonglin Luan*. Label-free liquid crystal biosensor for Cecropin B detection. Talanta, 2018, 186, 60-64. n Xue Wang, Chaohua Xue, Dong Yang, Shuntian Jia, Yaru Ding, Lei Lei, Keyi Gao, Tongtong Jia. Modification of a nitrocellulose membrane with nanofibers for sensitivity enhancement in lateral flow test strips [J]. RSC Advances. 2021, 11: 26493. 3. 专利 n 杨冬，王丽霞，雷蕾，高可奕，贾彤彤. 一种具有单分散和超顺磁性的金磁复合微球及制备方法. ZL 201910926931.7 n 杨冬, 王丽霞，雷蕾，高可奕，贾彤彤. 一种单分散、超顺磁性四氧化三铁纳米花及其制备方法. XL 2019109269181 n 杨冬. 一种自组装制备纳米级贵金属壳磁核复合微粒的方法. ZL201510464315.6
4. 获奖 n 杨冬. 基于Fe3O4@Au金磁纳米微粒的免疫探针构建及在即时检测中的应用研究，陕西省优秀博士论文，2017 |
